Monday, August 19, 2013

Exercise in Midlife May Prevent Dementia


The June 2013 Family Circle had a blurb about the benefits of exercise.  I do not usually read Family Circle magazine, but it came in the mailbox free and this article really caught my attention.  It said that people in midlife, in their 40’s and 50’s, who exercised regularly had less dementia later in life than those who did not exercise.  The article cited the Cooper Institute and so I went online and found the Cooper Institute website. It is a preventive non-profit medical clinic founded in the 1970’s in Dallas, Texas.  From there, I found the peer reviewed scholarly article that served as the foundation of the Family Circle article.  Here is the rest of the story:

The primary investigator on the research study was Dr. Laura DeFina, MD.  She and seven other physicians [and one PhD] looked at medical records and physical exams of patients at the Cooper Clinic who were patients there at midlife.  They examined 19,500 medical records from 1971-2009 and then Medicare claims of the same individuals from 1999-2009.  Then, they compared their Medicare claims years later to their midlife fitness levels.  The patients, who had physical exams at the Cooper Clinic, did not fill in the usual “self-report” about whether they exercised or not: They had treadmill tests that measured their fitness levels!

Here were the findings.  Patients who had higher levels of fitness at midlife had less dementia later in life.  In the U.S., approximately 24% of older adults have dementia.  The DeFina et al. (2013) study found that 14.8% of the high fitness level patients later developed dementia.  They found that patients with the highest levels of fitness in midlife had the lowest incidence of dementia later in life.  Why?  Exercise and fitness leads to better brain flow and larger brains.  

Who cares?  So what does this mean?  First, the DeFina (2013) study has high validity.  They examined thousands of records, the patients were measured for fitness –vs- self-reports, and they looked at records over a long period of time.  These findings can be generalized and/or extrapolated.  In non-academic lingo, this means it is a significant and we should pay attention. 

Second, this study has public health implications.  Dementia costs U.S. taxpayers $200 billion now and it is expected to grow to 1.1 trillion by 2050 unless programs are implemented to reduce the development of dementia.  Reducing dementia by exercising over the lifespan, and especially at midlife, is one step in the right direction and is something we can ALL do.    

Resource:
DeFina, L.F., Willis, B.L., Radford, N.B., Gao, A., Leonard, D., Haskell, W.L., Weiner, M.F., & Berry, J.D. (2013). The association between mid-life cardiorespiratory fitness and later-life dementia. Annals of Internal Medicine,158. 162-168.
















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