Monday, June 12, 2023

Today's Research on Aging and Sleep

 

Hi Readers, 

Here are some common questions I have been asked when speaking on this topic:

Q: “I am 80 and I take a one-hour nap after lunch. Is this why I can’t sleep at night?”

A: YES! A nap of more than 20 minutes will interfere with your sleep at night.

 

Q: “I am a senior. I never nap and I don’t believe in naps. I doze off several times daily while watching television. Why can’t I sleep at night?” 

A: You can’t sleep at night because you are sleeping during the day. Dozing is sleeping!!

 

Q: “I heard that seniors should get a good night’s sleep and that red wine is good for health. If I drink a glass of wine before bed, will that help me?”

A: Yes, it will help you fall asleep. BUT you will reawaken and have trouble getting to sleep again. Also, alcohol is dangerous if mixed with certain medications. One 6 oz. glass is the maximum amount of wine for an older adult per day. According to the latest research, there is no medical benefit to drinking alcohol at any age.

Do older adults get enough sleep? The public’s awareness of quality sleep is improving, but still not as stressed as it should be. Less than five hours per night raises the risk of death. According to a study of nearly 800 older adults aged 62-90 who reported insomnia and sleep deprivation, their perception of their sleep habits and their actual sleep did not match. They completed self-reports and then wore an electronic device [like a Fitbit] to measure length and type of sleep. The study findings showed that their average sleep time was 7.3-7.9 hours. 

The myth that older adults need less sleep as they age is not grounded in science. According to the NIH, older adults need the same amount of sleep as other adults, about 7-9 hours. 

Researchers are finding an association between sleep deprivation and chronic diseases. I attended a webinar on May 12 featuring Dr. Richard Bogan. Poor sleep and duration are associated with high blood pressure, elevated cholesterol, stroke, heart attack. The American Heart Association added SLEEP to its checklist for measuring cardiovascular health, as sleep quality is an essential component for heart and brain health.

In a study of 100 participants in Pennsylvania, sleep deprived older adults:

·      Ate 500 calories more per day (about 10 pounds yearly weight gain)

·      Slow reaction time

·      Poor attention span

·      Bad mood, negative facial expression

·      Low energy

·      Brain fog and forgetting

WHY were they sleep deprived? Frequent urination, pain, effects of medication, restless leg syndrome, napping, caregiving, computer screens, caffeine, worry, etc.

Sleep and chronic conditions – Disturbed sleep is associated with inflammation which is associated with biomarkers related to diabetes and cardiovascular disease. Treating insomnia can reduce inflammation, as shown in numerous studies. Modifiable risk factors are high fat diets and sedentary lifestyle.

Glymphatic Clearance is a term new to most people. What happens if your washing machine skipped the rinse cycle? Clothes would have suds and leave a soapy, sticky film. Recent studies have shown that during sleep, waste clearance occurs in the brain. It works like the rinse cycle of the washing machine. The glymphatic system is a fluid transport system and can be described as a rinsing network distributed throughout the brain. Although some glymphatic clearance occurs during waking hours, the vast majority of glymphatic clearance occurs during sleep while the brain is idle. It cleanses the brain during sleep, removing toxins, including Amyloid B associated with Alzheimer’s Disease. Researchers have found that sleeping on the right side of the body optimizes glymphatic clearance. These studies impact healthy brain aging and Alzheimer’s Disease research. In the References and Resources section below, access Dr. Collins’ video of glymphatic rinsing!

Does poor sleep cause depression in old age? Disturbed sleep is associated with depression, a treatable medical condition not to be confused with “mental illness.” People with depression have a higher number of chronic diseases including high blood pressure, diabetes, chronic lung disease, cardiovascular disease, cancer, arthritis. Does poor sleep cause depression? That is debatable but the most recent research suggests that depression is attributed to having chronic conditions.

Napping among older adults is quite common, especially if they are retired and have napping opportunities. People nap for a variety of reasons:

a.     Poor nighttime sleep

b.     Chronic conditions

c.      Sedating medications

d.     A boost in late-day fun

e.     A boost in later day functioning

f.       Less social engagement

g.      boredom

Short naps of under 90 minutes may be beneficial. Older adults taking longer naps (over 90 minutes) are more likely to restrict their participation in one or more valued activities.  

Caregiving takes a toll on sleep, especially dementia caregiving. The more aid caregivers provide, the more they are sleep deprived. Sometimes, extended family relationships impact sleep quality. Participants describe causes as stress, conflict, supportiveness, demands, concerns, and criticism. Likewise, family relationships may be beneficial or harmful to sleep.

Ethnicity and socioeconomic factors also impact sleep. Numerous studies show that African Americans who report high levels of discrimination also tend to sleep poorly. Participants reported they are treated with less respect, assumed to be dishonest or not smart, and people afraid of them because they are black. Researchers concluded that discrimination explains some of the sleep differences between African Americans and Whites. Living in a disadvantaged neighborhood contributes to less sleep. African Americans slept for less time, took longer to fall asleep, and woke after falling asleep more than other White Americans. Less sleep contributes to racial disparities in health.

The Sleep Foundation is an informative and practical website for developing strategies for getting more quality sleep, a term known as sleep hygiene. What you do during the day impacts how you sleep at night. Some sleep hygiene recommendations are:

a.          Wake up and go to bed at the same time every day including weekends.

b.             Limit naps.

c.              Ingest caffeine early in the day. The effects of caffeine stay in the body for twelve hours.

d.             Avoid alcohol, as it interrupts restorative sleep.

e.             Darkness promotes sleep. Therefore, keeping the room dark and wearing an eye mask secretes more melatonin, a hormone that induces sleepiness.

 

References and Resources:

The Sleep Foundation: https://www.sleepfoundation.org/aging-and-sleep

 

Collins, F. (March 5, 2020). Discovering the brain’s nightly rinse cycle. https://directorsblog.nih.gov/2020/03/05/discovering-the-brains-nightly-rinse-cycle/

 

Gulia, K.K. and Kumar, V.M. (2018). Sleep disorders in the elderly: a growing challenge. Psychogeriatrics, 18: 155-165. https://doi.org/10.1111/psyg.12319

 

Reddy OC, van der Werf YD. The sleeping brain: harnessing the power of the glymphatic system through lifestyle choices. Brain Sci. 2020 Nov 17;10(11):868. doi: 10.3390/brainsci10110868. PMID: 33212927; PMCID: PMC7698404

 

Improvements in knowledge of sleep and heart health. Richard Bogan, MD (May 11, 2023). Video. https://www.neurologylive.com/view/improvements-in-knowledge-sleep-and-heart-health-richard-bogan?utm_source=sfmc&utm_medium=email&utm_campaign=05172023_NRL_HAR-23-NRD0223_Narc%20MMCC_eNL%205-12&eKey=Z2V0ZHJqYW5AZ21haWwuY29t

 

 

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